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David W Fry Selected Research

Pharmaceutical Preparations

4/2005Discovery of a potent and selective inhibitor of cyclin-dependent kinase 4/6.
5/2002Drug-induced ubiquitylation and degradation of ErbB receptor tyrosine kinases: implications for cancer therapy.
1/2002Differential sensitivity of cancer cells to inhibitors of the epidermal growth factor receptor family.

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David W Fry Research Topics

Disease

11Neoplasms (Cancer)
07/2008 - 01/2002
3Carcinoma (Carcinomatosis)
02/2006 - 11/2004
2Glioblastoma (Glioblastoma Multiforme)
02/2006 - 06/2005
2Squamous Cell Carcinoma (Epidermoid Carcinoma)
02/2006 - 06/2005
2Breast Neoplasms (Breast Cancer)
10/2003 - 06/2002
1Adenocarcinoma
11/2012
1Urinary Bladder Neoplasms (Bladder Cancer)
06/2006
1Rhabdomyosarcoma
05/2006
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
06/2005
1Retinoblastoma (Glioblastoma, Retinal)
11/2004

Drug/Important Bio-Agent (IBA)

5ErbB Receptors (EGF Receptor)IBA
06/2005 - 01/2002
4Canertinib (CI 1033)IBA
06/2005 - 05/2002
3Cyclin-Dependent Kinase 4IBA
05/2006 - 11/2004
3Pharmaceutical PreparationsIBA
04/2005 - 01/2002
2Indicators and Reagents (Reagents)IBA
06/2006 - 06/2002
2MitogensIBA
05/2006 - 01/2002
2Tyrosine (L-Tyrosine)FDA Link
06/2005 - 05/2002
2Phosphotransferases (Kinase)IBA
06/2005 - 05/2002
2Cyclin-Dependent Kinases (cdk Proteins)IBA
04/2005 - 04/2005
2palbociclibIBA
04/2005 - 11/2004
2ErbB-2 ReceptorIBA
10/2003 - 06/2002
1ParaffinIBA
11/2012
1Formaldehyde (Formol)FDA Link
11/2012
1Gefitinib (Iressa)FDA Link
07/2008
1dacomitinibIBA
07/2008
1Erlotinib Hydrochloride (CP 358,774)FDA Link
07/2008
1Cyclin DIBA
05/2006
1Dihydrotachysterol (AT 10)IBA
02/2006
1pyrimidineIBA
02/2006
1Messenger RNA (mRNA)IBA
06/2005
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2005
1SaltsIBA
06/2005
1Mesylates (Mesylate)IBA
06/2005
1Biomarkers (Surrogate Marker)IBA
06/2005
1Interleukin-8 (Interleukin 8)IBA
06/2005
1Retinoblastoma ProteinIBA
11/2004
1Tyrosine Kinase InhibitorsIBA
05/2002
1NucleotidesIBA
05/2002
1geldanamycinIBA
05/2002
1Oncogene Proteins (Oncogene Protein)IBA
05/2002

Therapy/Procedure

3Oral Administration
07/2008 - 11/2004
3Therapeutics
06/2005 - 05/2002
2Drug Therapy (Chemotherapy)
10/2003 - 06/2002